Barinthus Bio considers options for VTP-200 program after failure

22 April 2024

Life under the name Barinthus Biotherapeutics (Nasdaq: BRNS) has not started well for the UK company formerly known as Vaccitech.

The Oxford-based biopharma changed its name last year to reflect the company’s new focus on developing novel T cell immunotherapeutic candidates designed to guide the immune system to overcome chronic infectious diseases, autoimmunity and cancer.

"While we didn’t observe a significant improvement from VTP-200 in the overall pooled results, we did observe positive trends in the highest dose cohorts"Last week, Barinthus announced top-line final data from the APOLLO trial, a completed randomized, placebo-controlled Phase Ib/II dose-ranging study of VTP-200 in women with low-grade cervical lesions associated with persistent high-risk human papillomavirus (hrHPV infection).

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