Aveo Oncology ties up with Pharmstandard for tivozanib in Russia, Ukraine and CIS

6 August 2015

US biotech firm Aveo Oncology (Nasdaq: AVEO) has entered into an exclusive license agreement with a subsidiary of Pharmstandard (PHST RU), the largest Russian pharmaceutical group.

The accord is for the development, manufacturing and commercialization of Aveo’s small molecule vascular endothelial growth factor (VEGF) tyrosine kinase inhibitor tivozanib in the territories of Russia, Ukraine and the Commonwealth of Independent States (CIS), for all indications excluding ocular conditions.

Aveo regained full rights to tivozanib, which has so far not received marketing approval in the USA, when Japan’s Astellas Pharma (TYO: 4503) terminated a three-year collaboration (The Pharma Letter February 14, 2014), following a number of research and regulatory disappoints with the drug.

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