AstraZeneca and Quell's Treg cell therapies deal in diabetes and IBD worth up to $2 billion

9 June 2023

Anglo-Swedish pharma major AstraZeneca (LSE: AZN) has entered into a collaboration, exclusive option and license agreement with privately-held UK biopharma Quell Therapeutics.

The deal is for the development of multiple engineered T-regulator (Treg) cell therapies that are seen to have the potential to be curative in type 1 diabetes (T1D) and inflammatory bowel disease (IBD) indications.

Under the terms of the agreement, Quell’s proprietary toolbox of Treg cell engineering modules, including its Foxp3 phenotype lock, will be leveraged to develop autologous multi-modular Treg cell therapy candidates for major autoimmune disease indications.

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