AstraZeneca and Peregrine expand ongoing immuno-oncology collaboration
US drugmaker Peregrine Pharmaceuticals (Nasdaq: PPHM) says it has expanded its ongoing cancer immunotherapy clinical collaboration with Anglo-Swedish pharma major AstraZeneca (LSE: AZN) to include a second, later-stage trial.
Financial terms of the new agreement were not revealed, but Peregrine’s shares moved 2.9% higher to $1.07 on the announcement today.
The companies will now also evaluate the immunotherapy combination of Peregrine’s phosphatidylserine (PS)-targeted immune-activator, bavituximab, and AstraZeneca’s anti-PD-L1 immune checkpoint inhibitor, durvalumab (MEDI4736), in a global Phase II study in patients with previously-treated squamous or non-squamous non-small cell lung cancer (NSCLC). The randomized Phase II trial will be conducted by Peregrine.
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