Detailed results have been presented from the NEURO-TTRansform Phase III trial in hereditary transthyretin-mediated amyloid polyneuropathy (ATTRv-PN) testing AstraZeneca (LSE: AZN) and Ionis’ (Nasdaq: IONS) eplontersen.
Following on from previously-announced positive results, the latest update is that eplontersen met all co-primary endpoints and secondary endpoints at 66 weeks versus an external placebo group.
"Eplontersen has a consistent and sustained treatment effect and reinforces its potential as an important medicine for the thousands of patients living with this debilitating and fatal disease"At 66 weeks, patients treated with eplontersen demonstrated consistent and sustained benefit on the three co-primary endpoints of serum transthyretin (TTR) concentration, neuropathy impairment and quality of life.
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