Aslan Pharmaceuticals is to develop and commercialize a new immuno-oncology antibody targeting RON (recepteur d’origine Nantais) after announcing a collaboration with Singapore’s Agency for Science, Technology and Research (A*STAR).
The Singapore-based biotech, which is focused on the development of immunotherapies and targeted agents for Asia-prevalent tumor types, has gained global rights to develop the RON antibody and intends to commence clinical studies in 2018. Commercial terms of the deal were not disclosed.
RON is a receptor tyrosine kinase and an overexpression of RON leads to increased tumor metastasis. Consequently, RON activation in tumor cells promotes aggressive disease.
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