ASCO 2024: Treos Bio vaccine shows potential again

4 June 2024

Treos Bio, a biotech using data science and proprietary biomarkers to develop precision peptide immunotherapies, has presented results from its Phase II OBERTO-301 study.

The trial is assessing the company’s lead product candidate, PolyPEPI1018, alongside atezolizumab in late-stage microsatellite stable metastatic colorectal cancer (MSS mCRC).

PolyPEPI1018 is an off-the-shelf, multi-peptide vaccine that has previously demonstrated the ability to induce immunological responses at both the peripheral and tumor levels, effectively turning immunologically ‘cold’ tumors into ‘hot’ ones.

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