Arrowhead Pharma refocuses, dropping lead hepatitis B candidates

30 November 2016

Arrowhead Pharmaceuticals’ (Nasdaq: AEWR) shares dropped 62.4% to $1.65 after hours on Tuesday after the company announced a refocusing of its research priorities, which includes dropping some programs.

Arrowhead will discontinue development of three clinical stage hepatitis treatments candidates ARC-520, ARC-521, and ARC-AAT, which utilize the DPCiv, or EX1, delivery vehicle.

Arrowhead remains committed to finding therapeutic options for patients with chronic hepatitis B (HBV) infection and alpha-1 antitrypsin deficiency (AATD). The company intends to advance to the clinic two previously unannounced HBV and AATD programs using our subQ platform. The company says it has learned a great deal during prior HBV and AAT studies that will help drive the subQ programs efficiently.

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