LifeArc revealed that its portfolio company Ducentis BioTherapeutics, a pre-clinical-stage UK biotechnology company focused on developing novel therapies for inflammation and autoimmune diseases, has been acquired by Arcutis Biotherapeutics (Nasdaq: ARQT), a California, USA-based early commercial stage biopharmaceutical company developing innovations in immuno-dermatology.
LifeArc was Ducentis’ largest investor, recognizing the transformational potential of its science and supporting its early translational research. Arcutis shares closed up 2% at $21.54 following the announcement on Wednesday.
Ducentis’ lead pre-clinical asset, DS-234, is being developed for the treatment of atopic dermatitis, a rapidly growing, significantly underserved market. DS-234 is a fusion protein that is a highly selective and potent agonist of CD200R, an immune-regulatory receptor thought to be an important immunological checkpoint, with a pivotal role in maintenance of immune tolerance.
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