Antibody technology from arGEN-X takes step forward

12 September 2013

Belgium-based preclinical stage biotech firm arGEN-X has generated potent antibody antagonists of Nav1.7 using its proprietary SIMPLE Antibody technology.

Nav1.7 has been validated as a therapeutic target in chronic pain, yet no antibody-based antagonists have been developed to date. Drugs targeting ion channels such as Nav1.7 require exquisite target selectivity and specificity to avoid unwanted side effects, which makes antibodies a preferred and highly desirable class of drug.

How the antibodies work

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