Massachusetts, USA-based biotechnology start-up Anchor Therapeutics has entered into a collaboration and license agreement with Ortho-McNeil-Janssen Pharmaceuticals, a unit of drug major Johnson & Johnson (NYSE: JNJ), with the goal of developing G protein coupled receptor (GPCR)-targeted therapeutic compounds utilizing Anchor's proprietary pepducin technology targeting oncology and metabolic disease.
Under the agreement, Anchor and OMJPI will work jointly to discover and optimize preclinical development candidates against GPCR targets in oncology and metabolic disorders, including Anchor’s program targeting gpr39, a GPCR involved in metabolic diseases. Ortho-McNeil will assume responsibility for development and commercialization. Anchor will receive an undisclosed upfront payment and research support and could be eligible for development and regulatory milestone payments up to $480 million.
Pepducin technology
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