US biotech giant Amgen (Nasdaq: AMGN) today announced that Kyprolis (carfilzomib) in combination with lenalidomide and dexamethasone is now available in the UK for the treatment of adult patients with multiple myeloma who have received at least one prior therapy.
Carfilzomib is the first licensed irreversible proteasome inhibitor for use in combination treatment of patients with relapsed multiple myeloma.
The European Commission licensed carfilzomib in combination with lenalidomide and dexamethasone based on the ASPIRE study last year The Pharma Letter 11, November 2015). Carfilzomib has shown significant improvement in progression-free survival (PFS) compared to lenalidomide and dexamethasone, reinforcing the belief that it may provide a new treatment option for patients with relapsed multiple myeloma.
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