Amgen's AMG 334 meets endpoint in prevention of episodic migraine

15 May 2015

US biotech major Amgen (Nasdaq: AMGN) has released the first results from its global Phase II, double-blind, placebo-controlled study evaluating the efficacy and safety of AMG 334 for the prevention of episodic migraine.

The study met its primary endpoint of reducing monthly mean migraine days compared with placebo. The data were presented at the 17th Congress of the International Headache Society (IHC 2015) in Valencia, Spain. AMG 334 is a fully human monoclonal antibody under investigation for the prevention of migraine by inhibiting the calcitonin gene-related peptide (CGRP) receptor that is believed to transmit signals that can cause incapacitating pain.

Trial details

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