Amgen and Sanofi hit back on PCSK9 price criticisms

18 August 2016

The makers of two cholesterol-lowering drugs have responded to a report which said that their products were not cost-effective and called for their US price to be cut by at least 68%.

An article in the Journal of the American Medical Association (JAMA) looked at the cost-effectiveness of recently-approved proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for lowering low-density lipoprotein cholesterol in heterozygous familial hypercholesterolemia (FH) or atherosclerotic cardiovascular disease (ASCVD).

The drugs analyzed were Repatha (evolocumab), marketed by US biotech major Amgen (Nasdaq: AMGN), and Praluent (alirocumab), from French pharma Sanofi (Euronext: SAN) and the USA’s Regeneron (Nasdaq: REGN).

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