Alzheimer's outsiders call for focus on toxic amyloid beta

22 March 2019

In the wake of the shocking failure of Biogen (Nasdaq: BIIB) and Eisai's (TYO) 423) aducanumab in Alzheimer’s, Canadian toxic oligomer specialist ProMIS Neurosciences (TSX: PMN) has called for attention to be paid to its favored therapeutic approach.

Chief medical officer James Kupiec, former head of Pfizer’s now-abandoned Alzheimer’s program, said: “Aducanumab wasted too much limited ammunition on the wrong target, which also led to the dose limiting side effect of brain swelling.”

For many years, debate has raged in the dementia community around the precise pathology of neurological conditions such as Alzheimer’s disease.

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