Alnylam links with Novartis on targeted therapy to restore liver function

7 January 2022

RNAi therapeutics company Alnylam Pharmaceuticals (Nasdaq: ALNY) closed down 2.6% at $151.00 yesterday, after it revealed it has entered a collaboration with Swiss pharma giant Novartis (NOVN: VX) to leverage Alnylam’s proven, proprietary siRNA technology to inhibit a target discovered at the Novartis Institutes for BioMedical Research, potentially leading to development of a treatment designed to promote the regrowth of functional liver cells and to provide an alternative to transplantation for patients with liver failure.

“We are so pleased to collaborate with Novartis,” said Kevin Fitzgerald, chief scientific officer at Alnylam. “We believe collaborations like this serve as an excellent example of how Alnylam's leadership in RNAi can fuel new frontiers of medicine with highly innovative targets coming from some of the most admired pharmaceutical companies,” he noted.

Liver transplantation currently the only treatment for ESLD

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