Alnylam enters the big time as patisiran excels in cardiomyopathy

3 August 2022

US RNAi therapeutics pioneer Alnylam Pharmaceuticals (Nasdaq: ALNY) looked set to close Wednesday’s New York trading with gains in excess of 40%.

The Boston-based company announced that the APOLLO-B Phase III study of patisiran, an investigational RNAi therapeutic in development for the treatment of transthyretin-mediated (ATTR) amyloidosis with cardiomyopathy, met the primary endpoint of change from baseline in the six-minute walk test (6-MWT) at 12 months compared to placebo.

"We see this result as a clean hit"

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