US biotech Alnylam Pharmaceuticals (Nasdaq: ALNY) cemented its standing as the leading RNAi therapeutics company on Tuesday by presenting positive Phase III data on its latest candidate.
Following in the footsteps of Alnylam’s two approved therapies, lumasiran met all primary and secondary tested endpoints in the ILLUMINATE-A study in primary hyperoxaluria type 1 (PH1), with significant reduction in urinary oxalate levels relative to placebo.
Based on these results, Alnylam plans to submit a New Drug Application in the USA and file a Marketing Authorisation Application to the European Medicines Agency for lumasiran in early 2020.
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2024 | Headless Content Management with Blaze