Alligator and BioInvent to begin trials of ADC-1015 in immuno-oncology

8 July 2016

Privately-held biotech Alligator Bioscience has brought in fellow Swedish company BioInvent International (STO: BINV) to do the process development and manufacturing of its immuno-oncology drug candidate ADC-1015.

This will allow Alligator to start early clinical trials of this candidate, which is a bispecific immune-activating antibody that targets OX40 and CTLA-4.

Since both OX40 and CTLA-4 are expressed on T cells in the tumor area, ADC-1015 is expected to induce strong tumor-directed immune activation.

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