Alexion on a roll with more good data for ultra-rare disease candidate

8 May 2018

Alexion Pharmaceuticals (Nasdaq: ALXN) has revealed new Phase III study results for ALXN1210, an investigational long-acting C5 inhibitor the firm is trialling against a serious ultra-rare blood disorder called paroxysmal nocturnal hemoglobinuria (PNH).

The study is designed to compare the efficacy and safety of ALXN1210 with Soliris (eculizumab), a monoclonal antibody the firm has developed for use against multiple blood disorders.

The study shows that patients can be effectively and safely switched from treatment with Soliris every two weeks to treatment with ALXN1210 every eight weeks.

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