Alexion joins forces with Dutch biotech on neurodegenerative disorders
US drugmaker Alexion Pharmaceuticals (Nasdaq: ALXN) has entered into a partnership with Dutch biotech Complement Pharma to co-develop the preclinical C6 complement inhibitor CP010 for neurodegenerative disorders.
C6 inhibition prevents the formation of the destructive membrane attack complex (MAC), a complex of terminal complement proteins that mediate cellular injury following complement activation, and has the potential to treat a variety of central nervous system disorders. Under the terms of the agreement, Alexion will provide Complement Pharma with up to 14 million euros ($16.5 million) in milestone-dependent payments through Phase Ib development.
The agreement also provides Alexion with the option to acquire Complement Pharma during the term of the agreement for an unspecified sum.
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