Affibody ends Alexion-partnered program

15 June 2020

Swedish company Affibody has announced the termination of its ABY-039 (FcRn) program in rare autoimmune diseases.

The company had just completed a Phase I study investigating safety, tolerability, pharmacokinetics, and pharmacodynamics of the bivalent antibody-mimetic that targets the neonatal Fc receptor.

Affibody’s main competitor, Argenx’ (EBR: ARGX) efgartigimod, has recently demonstrated the benefit of IgG lowering in patients with myasthenia gravis in Phase III.

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