Adverse events seen at higher dose but Magenta trial to continue

21 December 2022

US clinical-stage biotech Magenta Therapeutics (Nasdaq: MGTA) has halted dosing in one of the groups taking part in a Phase I/II study of cancer candidate MGTA-117.

The announcement on Tuesday halved the value of shares in the company, as investors fretted over the implications for the targeted conditioning agent.

Magenta is developing the candidate for people with genetic diseases, for administration prior to delivery of ex vivo gene therapies.

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