Adjuvant Opdivo shows superiority to Yervoy in resected high-risk melanoma

5 July 2017

US pharma major Bristol-Myers Squibb (NYSE: BMY) has announced results from a Phase III study comparing Opdivo (nivolumab) to Yervoy (ipilimumab) in stage IIIb/c or stage IV melanoma who are at high risk of recurrence following complete surgical resection.

The CheckMate -238 trial met its primary endpoint at a planned interim analysis, demonstrating superior recurrence-free survival (RFS) in patients receiving Opdivo compared to Yervoy.

Both drugs belong to B-MS, where Vicki Goodman is development lead for melanoma and genitourinary cancers.

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