Actelion seeks partner for its promising antimalarial compound
Swiss biotech firm Actelion (SIX: ATLN) announced today that a series of recently published scientific articles describing the unique profile of the company's orally-active antimalarial compound, ACT-451840, has reinvigorated interest in the compound.
As a result, Actelion says it is in discussions to find a partner with the expertise and resources to bring this promising therapy to patients.
ACT-451840 appears to have a distinct mode of action that sets it apart from current antimalarial drugs, including artemisinins. It has a rapid onset of action as well as activity on all blood-borne (erythrocytic) stages, which is retained against multiple resistant parasites, including artemisinin-resistant strains. Unlike the majority of antimalarial agents, ACT-451840 has the potential to block disease transmission due to its activity on gametocytes.
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