Actelion gives the good news with the bad on cadazolid trials

8 June 2017

In a brief press release, Actelion Ltd (SIX: ATLN) gave mixed news from its pivotal program comparing novel anti-infective cadazolid with the antibiotic vancomycin as a treatment for clostridium difficile-associated diarrhea (CDAD).

While one Phase III trial met its primary endpoint, a second did not. The company says the drug displayed “an acceptable tolerability and safety profile.”

The drug, which is described as a novel quinoxolidinone antibiotic, is designed to inhibit clostridium difficile protein synthesis, leading to suppression of toxin production and spore formation.

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