Achilles Thera shifts focus to new cancer treatment avenues
Achilles Therapeutics (Nasdaq: ACHL) has announced it will discontinue its tumor-infiltrating lymphocyte (TIL)-based clonal neoantigen T cell (cNeT) program and shut down its Phase I/IIa CHIRON and THETIS trials.
The shift follows disappointing interim data from the CHIRON trial in advanced non-small-cell lung cancer and the THETIS trial in melanoma, which failed to meet expectations.
Despite the setback, Achilles is seeking to expand its efforts in targeting clonal neoantigens, leveraging its technology platform to explore alternative approaches.
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