Swiss biopharma company AC Immune has announced a collaboration with US biotech major Biogen (Nasdaq: BIIB) to develop PET-ligands for two protein targets involved in pathogenesis of neurodegenerative diseases.
The companies will further research, develop and clinically validate an alpha-synuclein PET radioligand that will be used as an imaging biomarker for Parkinson’s disease and related synucleinopathies to develop new disease-modifying therapies.
They will also pursue a new research program to identify and develop novel PET radioligands for TDP-43, a recently identified target of growing interest in the pathogenesis of neurodegenerative diseases such as amyotrophic lateral sclerosis - Lou Gehrig’s disease.
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