US drugmaker AbbVie (NYSE: ABBV) has teamed up with a UK drug discovery and development company focused on selectively targeting deubiquitylating enzymes (DUBs).
The deal with privately-held UK biotech Mission Therapeutics is a collaboration in the research and preclinical development of specified DUB inhibitors for the treatment of Alzheimer’s and Parkinson’s diseases.
There is optimism in Mission’s work in these hard-to-treat conditions because DUBs play an important role in keeping a cell healthy by regulating the degradation of the misfolded, toxic proteins that are believed to cause impaired function and death of nerve cells in the brain.
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