AbbVie takes over development of cystic fibrosis research program
US biopharma firm AbbVie (NYSE: ABBV) will assume full development and commercial responsibility for its collaboration with Belgo-Dutch biotech Galapagos (Euronext: GLPG) to discover and develop new therapies to treat cystic fibrosis (CF).
AbbVie's research program aims to develop a best-in-class, triple-combination therapy for patients living with cystic fibrosis. Currently in early clinical development, the program consists of mechanistically distinct drug-candidates, termed "potentiators" and "correctors," which collectively increase the activity of the mutated copies of the cystic fibrosis transmembrane conductance regulator (CFTR) protein that causes CF.
AbbVie will apply its expertise in medicinal chemistry and small-molecule drug discovery and development to produce promising candidates that will help change the standard of care for CF patients.
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