AbbVie adds to data supporting Imbruvica in CLL and SLL

7 June 2016

US pharma major AbbVie (NYSE: ABBV) has announced longer-term follow-up results from Phase III studies of Imbruvica (ibrutinib) in chronic lymphocytic leukemia and small lymphocytic lymphoma (CLL/SLL).

The findings, which were presented at the 2016 American Society of Oncology (ASCO) Annual Meeting, include an analysis of outcomes from the RESONATE and RESONATE-2 trials, which showed Imbruvica was associated with favorable progression-free survival (PFS) and overall survival (OS) regardless of line of therapy.

Other data includes first-ever follow-up data from the HELIOS trial, which showed that Imbruvica in combination with bendamustine and rituximab (BR) continued to demonstrate superiority over time versus placebo plus BR in relapsed/refractory CLL/SLL patients. Improvements in quality of response were also noted.

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