89bio latest to offer encouragement in NASH

22 March 2023

Shares in liver and cardiometabolic diseases specialist 89bio (Nasdaq: ETNB) shot up by around a quarter in Wednesday morning’s trading.

The US biopharma firm had earlier announced positive top-line data from the Phase IIb ENLIVEN trial evaluating treatment with pegozafermin in patients with nonalcoholic steatohepatitis (NASH).

Both the 44mg every-two-week and 30mg weekly doses met, with high statistical significance, the primary histology endpoints per the US Food and Drug Administration (FDA) guidance on endpoints and statistical analysis.

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