US biopharma Biohaven has provided an update regarding the taldefgrobep alfa development programs in spinal muscular atrophy (SMA) and obesity.
In the RESILIENT SMA study, taldefgrobep alpha showed-clinically meaningful improvements in motor function at all timepoints on the motor function measurement-32 scale (MFM-32), but the treatment arm did not statistically separate on the primary outcome at week 48 compared to the placebo and standard of care (SOC) group.
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