Avidity jumps on breakthrough in Duchenne research
US RNA-focussed biotech Avidity Biosciences (Nasdaq: RNA) saw is shares close up more than 12% at $46.95 on Friday, after it announced positive AOC 1044 5mg/kg data demonstrated unsurpassed delivery of phosphorodiamidate morpholino oligomers (PMO) concentrations to skeletal muscle in Duchenne muscular dystrophy (DMD) patients.
Avidity also announced delpacibart zotadirsen as the approved international non-proprietary name of AOC 1044, abbreviated as del-zota.
In the Phase I/II EXPLORE44 study, del-zota demonstrated:
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