Athira shifts focus to ALS drug after Alzheimer’s flop
US clinical stage CNS drug developer Athira Pharma (Nasdaq: ATHA) is taking decisive action following the company’s announcement of disappointing data from the Phase II/III LIFT-AD clinical trial of fosgonimeton to treat Alzheimer’s disease (AD).
Neither the trial's primary endpoint nor its key secondary endpoints were met, sending shares in Athira tumbling by more than 78% in a single day.
The company plans to focus on advancing the clinical development program for ATH-1105 as a potential treatment for neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS) and AD.
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