Strong Phase III Xtandi data could give Pfizer and Astellas a boost

6 February 2018
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Japan’s Astellas Pharma (TYO: 4503) and development partner Pfizer (NYSE: PFE) have made public the data powering US and EU regulatory submissions for Xtandi (enzalutamide) in prostate cancer.

Data from the Phase III PROSPER trial show that adding treatment with the androgen receptor inhibitor to regular hormone therapy reduced the risk of metstases or death by 71%.

Analysts believe the strong efficacy data could impact significantly on prescribing practices for Xtandi, which was the chief attraction in the portfolio of Medivation, the San Franciscan biotech acquired by Pfizer for $14 billion in 2016.

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