Sanofi rebuffed by UK HTA over Dupixent for atopic dermatitis

3 April 2018
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The UK’s health technology assessor has issued draft guidance that does not recommend Dupixent (dupilumab) for routine use to treat moderate-to-severe atopic dermatitis, a condition which affects about 1.5 million adults in the country.

The guidance from the National Institute for Health and Care Excellence (NICE), if finalized, will mean that the therapy is not used routinely by the UK’s national healthcare provider, the National Health Service.

The drug was approved for AD in September last year, on the strength of data from the Phase III LIBERTY AD CHRONOS trial, which showed Dupixent, together with topical corticosteroids had a positive effect compared with placebo.

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