Promise of Pliant's bexotegrast sends shares surging

24 January 2023

Pliant Therapeutics (Nasdaq: PLRX), a Californian biopharma focused on discovering and developing fibrosis drugs, closed up by more than a third on Monday.

On Sunday, the company had announced 12-week interim data from the 320mg dose group of INTEGRIS-IPF, a Phase IIa trial of bexotegrast in idiopathic pulmonary fibrosis (IPF).

"Unprecedented in clinical trials observed to date"This trial is evaluating bexotegrast at once-daily doses of 40mg, 80mg, 160mg, 320mg or placebo for 12 weeks in 119 patients with IPF.

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