Pioneer ALK blocker breaks new ground with rare cancer nod

15 July 2022

In the USA, a new approval for Xalkori (crizotinib) will extend the first-generation ALK inhibitor’s use to include certain people with myofibroblastic tumors.

The US Food and Drug Administration has granted approval for adults and children over one with unresectable, recurrent, or refractory inflammatory ALK-positive tumors of this type.

The decision is based on results from two multicenter, single-arm, open-label trials, showing a clinical benefit in terms of objective response rate (ORR).

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