German vaccines developer CureVac (Nasdaq: CVAC) saw its shares halve in value overnight, after the firm announced its coronavirus vaccine had failed late-stage testing.
The company is developing mRNA-based vaccines for the novel coronavirus, and has already secured considerable interest from governments, including a 50 million dose order from the UK.
Now the program appears in doubt, after results from the second interim analysis of its pivotal Phase IIb/III study showed vaccine efficacy of 47%, below the level required for statistical success.
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