More bad news for selonsertib, but Gilead undeterred in NASH
Two months after announcing a Phase III flop for selonsertib, one of its key non-alcoholic steatohepatitis (NASH) candidates, US biotech Gilead Sciences (Nasdaq: GILD) says the drug has failed another pivotal test.
Top-line data show the STELLAR-3 study did not meet its primary endpoint, with just 9.3% of people treated with selonsertib at the higher dose, and 12.1% at the lower dose, achieving the required improvement. 13.2% of people in the placebo group met that threshold.
The firm has invested significantly in building a pipeline of NASH drugs, hoping to gain a share of what analysts expect to become a multi-billion dollar market in future years.
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