Lymphoma drug submission from Ono banking on Phase I/II study

29 August 2019
ono-big

Ono Pharmaceutical (TYO: 4528) is relying on data from a Phase I/II study in 44 patients with its application for manufacturing and marketing approval of tirabrutinib hydrochloride to treat recurrent or refractory primary central nervous system lymphoma (PCNSL) in Japan.

Only last month, the Japanese Ministry of Health, Labour and Welfare granted the Bruton’s tyrosine kinase (BTK) inhibitor orphan drug status in PCNSL, a malignant lymphoma in which the lesion is localized in the cerebrospinal cord at the first onset.

High level of unmet need

This article is accessible to registered users, to continue reading please register for free.  A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.

Login to your account

Become a subscriber

 

£820

Or £77 per month

Subscribe Now
  • Unfettered access to industry-leading news, commentary and analysis in pharma and biotech.
  • Updates from clinical trials, conferences, M&A, licensing, financing, regulation, patents & legal, executive appointments, commercial strategy and financial results.
  • Daily roundup of key events in pharma and biotech.
  • Monthly in-depth briefings on Boardroom appointments and M&A news.
  • Choose from a cost-effective annual package or a flexible monthly subscription
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed

Chairman, Sanofi Aventis UK

Companies featured in this story

More ones to watch >


Today's issue

Company Spotlight





More Features in Biotechnology