J&J nasal spray set to win first approval in ketamine-based depression research

13 February 2019
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US healthcare giant Johnson & Johnson (NYSE: JNJ) has been buoyed by a positive decision from the advisory panel of the US regulator on the firm’s experimental depression therapy Spravato (esketamine).

The fast-acting antidepressant, administered through a nasal spray, is thought to work differently than currently approved therapies for major depressive disorder (MDD).

A close relative of the anaesthetic ketamine, the therapy, under development by J&J’s pharmaceutical unit Janssen, is being hailed as the first new type of product for MDD in decades.

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