Bristol-Myers and Clovis trial new combo therapy in multiple oncology indications

1 August 2017

New York-based Bristol-Myers Squibb (NYSE: BMY) will collaborate with Clovis Oncology (Nasdaq: CLVS) to test a new combination therapy, Opdivo (nivolumab) plus Rubraca (rucaparib).

The companies plan to launch Phase III trials in the USA and Europe this year, exploring the combination as a first-line maintenance therapy in ovarian and breast cancer, as well as a Phase II trial in prostate cancer.

Rubraca is a small molecule which inhibits PARP, a particular enzyme, indicated in the USA for use against ovarian cancer. In March, the company presented data on a trial investigating the drug in this therapeutic area.

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