BRIEF—AstraZeneca buys global rights to novel KRAS inhibitor

24 November 2023

British pharma major AstraZeneca has in-licensed a KRAS blocker, currently codenamed UA022, from Chinese biotech Usynova.

The terms of the deal include a $24 million upfront payment, plus up to around $400 million in development and commercial milestones, plus royalties on sales, in return for global development rights.

Furthering its push into oncology, AstraZeneca is looking to follow pioneering medicines in this class, such as Lumakras (sotorasib), from Amgen (Nasdaq: AMGN), and Krazati (adagrasib), from Mirati Therapeutics (Nasdaq: MRTX).

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