BridgeBio out-licenses infigratinib in Japan

7 February 2024
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California, USA-based biotech BridgeBio Pharma (Nasdaq: BBIO) today announced a partnership wherein its affiliate, QED Therapeutics, grants Japan’s Kyowa Kirin (TYO: 4151) an exclusive license to develop and commercialize infigratinib for achondroplasia, hypochondroplasia, and other skeletal dysplasias in Japan.

In exchange, BridgeBio will receive an upfront payment of $100 million as well as royalties up to the high-twenties percent on sales of infigratinib in Japan, with the potential for additional milestone-based payments. Infigratinib is an oral small molecule designed to inhibit FGFR3 and thus target FGFR3-driven skeletal dysplasias at their source, including achondroplasia and hypochondroplasia.

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