Merck KGaA (MRK: DE) and Pfizer’s (NYSE: PFE) entry into the PD-L1 space has secured a European Commission approval in combination with axitinib for the first-line treatment of adult patients with advanced renal cell carcinoma (RCC).
The approval of the Bavencio (avelumab) combination comes nearly six months after it was approved by the US Food and Drug Administration in this indication.
Positive interim results from the Phase III JAVELIN Renal 101 study helped to secure the approval, demonstrating that Bavencio and axitinib significantly lowered risk of disease progression or death by 31% compared with sunitinib in patients with advanced RCC regardless of PD-L1 status.
This article is accessible to registered users, to continue reading please register for free. A free trial will give you access to exclusive features, interviews, round-ups and commentary from the sharpest minds in the pharmaceutical and biotechnology space for a week. If you are already a registered user please login. If your trial has come to an end, you can subscribe here.
Login to your accountTry before you buy
7 day trial access
Become a subscriber
Or £77 per month
The Pharma Letter is an extremely useful and valuable Life Sciences service that brings together a daily update on performance people and products. It’s part of the key information for keeping me informed
Chairman, Sanofi Aventis UK
Copyright © The Pharma Letter 2024 | Headless Content Management with Blaze