Amgen’s MariTide falls short of analyst expectations in obesity
Shares in US biotech major Amgen were 11% lower early on Tuesday, despite positive trial data.
The Californian company earlier announced positive data at 52 weeks in a double-blind, dose-ranging Phase II study with MariTide (maridebart cafraglutide, formerly AMG 133), an investigational antibody peptide conjugate subcutaneously administered monthly or less frequently.
In people living with obesity or overweight without type 2 diabetes, MariTide demonstrated an up to 20% average weight loss at week 52 without a weight loss plateau, indicating the potential for further weight loss beyond 52 weeks.
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