Aditum and Leads Biolabs form new company, Oblenio Bio

7 November 2024

US biotech venture fund Aditum Bio and China’s Leads Biolabs today announced the formation of Oblenio Bio, marking the thirteenth company launched by Aditum.

They explain that the new firm is being formed in conjunction with an exclusive option and license agreement to develop LBL-051, a first-in-class CD19xBCMAxCD3 tri-specific T-cell engager antibody for autoimmune diseases. Aditum Bio will fund Oblenio Bio and the parties will collaborate to rapidly bring LBL-051 into clinical studies.

Recent clinical data from CD19 and BCMA targeted therapies have demonstrated compelling efficacy in difficult-to-treat autoimmune diseases. Despite these promising results, there is a continued unmet need for increased efficacy and durability. By targeting both CD19 and BCMA, LBL-051 has the potential to deliver stronger and more durable responses by depleting a broader range of pathological B-cell populations across a wide spectrum of antibody-mediated autoimmune diseases.

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