AbbVie’s costly schizophrenia failure sends BMS the other way
US drugmaker AbbVie (NYSE: ABBV) was trading more than 11% lower early on Monday afternoon in New York.
The Chicago-based firm earlier announced that its two Phase II EMPOWER trials investigating emraclidine as a once-daily, oral monotherapy treatment for adults with schizophrenia who are experiencing an acute exacerbation of psychotic symptoms, did not meet their primary endpoint.
In the trials, the targeted endpoint was to show a statistically significant reduction in the change from baseline in the positive and negative syndrome scale (PANSS) total score compared to the placebo group at week six. This was not achieved.
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